Value of Urinary ACR and CN1 in the Diagnosis of Early Diabetic Nephropathy
Objective To explore the value of urinary ACR and CN1 in the diagnosis of early diabetic nephropathy(DN).Methods 90 DN patients were selected as the observation group,and 90 healthy people were selected as the control group.The urinary ACR and CN1,and renal function indicators were compared between the two groups.The correlations between urinary ACR,CN1 and renal function indicators in DN patients and the diagnostic value for DN were analyzed.Results The levels of urinary ACR and CN1,and serum Scr,BUN,AA and CysC in the observation group were higher than those in the control group(P<0.05).Urinary ACR and CN1 were positively correlated with Scr,BUN,AA and CysC(P<0.05).The AUC of combined detection of urinary ACR and CN1 in the diagnosis of DN was higher than that of ACR and CN1 alone(P<0.05).Conclusions The expressions of urinary ACR and CN1 in patients with early DN increase and are correlated with renal function indicators.Combined detection of the two can improve the diagnostic value for early DN.
国家科技期刊平台
NSTL
万方数据
维普
