Clinical Study on Conbercept Combined with Panretinal Laser Photocoagulation in the Treatment of Patients with Ischemic Central Retinal Vein Occlusion
Objective To analyze the clinical effect of conbercept combined with panretinal laser photocoagulation in the treatment of patients with ischemic central retinal vein occlusion(CRVO).Methods 80 patients with ischemic CRVO were randomly divided into two groups equally.The control group was treated with panretinal laser photocoagulation,and the study group was treated with conbercept combined with panretinal laser photocoagulation.Both groups were followed up for 3 months.The treatment effect,BCVA,CMT and vascular endothelial function of the two groups were compared.Results The total effective rate of treatment in the study group was 97.50％,higher than 77.50％in the control group(P＜0.05).3 months after treatment,the BCVA of the study group was higher than that of the control group,and the CMT was lower than that of the control group(P＜0.05).3 d after treatment,the NO level of the study group was higher than that of the control group,and the VEGF and ET-1 levels were lower than those of the control group(P＜0.05).Conclusions Conbercept combined with panretinal laser photocoagulation has significant effect in the treatment of patients with ischemic CRVO,which can significantly improve the vascular endothelial function,and promote the recovery of visual acuity and the regression of macular edema.
Ischemic central retinal vein occlusionConberceptPanretinal laser photocoagulationClinical efficacy
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