Clinical Study on Salbutamol Combined with Budesonide Aerosol Inhalation in the Treatment of Children with Asthmatic Pneumonia
Objective To explore the clinical effect of salbutamol combined with budesonide aerosol inhalation in the treatment of children with asthmatic pneumonia(AP)and the impact on the serum INF-γ,IL-4 and IL-10 levels.Methods 116 AP children were selected and randomly divided into combined group and control group,with 58 cases in each group.The control group was treated with salbutamol aerosol inhalation,and the combined group was treated with salbutamol combined with budesonide aerosol inhalation.Both groups were treated continuously for 7 days.The clinical efficacy,the serum INF-y,IL-4 and IL-10 levels,and adverse reactions were compared between the two groups.Results The total effective rate of treatment in the combined group was 93.10％,higher than 79.31％in the control group(P＜0.05).After 7 days of treatment,the serum INF-y level of the combined group was higher than that of the control group,and the IL-10 and IL-4 levels were lower than those of the control group(P＜0.05).The incidence of adverse reactions during treatment in the combined group was 8.62％,which had no statistical difference with 3.45％ of the control group(P＞0.05).Conclusions Salbutamol combined with budesonide aerosol inhalation in the treatment of AP children can significantly improve the clinical efficacy,improve the serum INF-y,IL-4 and IL-10 levels of children,and is safe and reliable.
Children with asthmatic pneumoniaSalbutamolBudesonideAerosol inhalation
国家科技期刊平台
NSTL
万方数据
