Effect of Dapagliflozin Combined with Routine Drugs on T2DM Complicated with Coronary Heart Disease and the Influence on Patients'Cardiac Function
Objective To explore the effect of dapagliflozin combined with routine drugs in the treatment of type 2 diabetes mellitus(T2DM)complicated with coronary heart disease(CHD)and the influence on patients'cardiac function.Methods 86 patients with T2DM complicated with CHD admitted to our hospital from September 2021 to May 2023 were selected and divided into two groups according to randomization method.The control group was treated with routine drugs,and the observation group was treated with dapagliflozin on the basis of the control group.The NYHA grading,HbA1c,hs-CRP and cardiac function indicators were compared between the two groups.Results After 3 months of treatment,the cardiac function of the observation group was better than that of control group(P＜0.05);The HbA1c,hs-CRP and NTproBNP levels of both groups decreased,and the HbA1c,hs-CRP and NTproBNP levels of the observation group were lower than those of the control group(P＜0.05).Conclusions Dapagliflozin combined with routine drugs in the treatment of T2DM patients complicated with CHD can reduce the blood glucose,inhibit the secretion of inflammatory factors and improve the cardiac function.
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