Impact of Tigecycline on Levels of Serum Inflammatory Factors of Patients with Multidrug-Resistant Acinetobacter Bau-mannii Pneumonia
Objective To explore the clinical effect of tigecycline in the adjuvant treatment of patients with multidrug-resistant Acinetobacter Baumannii(AB)pneumonia.Methods 112 patients with multidrug-resistant AB pneumonia were randomly divided into two groups.The control group was treated with cefoperazone sulbactam,and the observation group was treated with tigecycline on the basis of the control group.The therapeutic effects of the two groups were compared.Results After treatment,the total effective rate and bacterial clearance rate of the observation group were higher than those of the control group,and the levels of WBC,CRP,and PCT were lower than those of the control group(P＜0.05).No significant difference was found in the incidence of adverse reactions between the two groups(P＞0.05).Conclusions Tigecycline in the adjuvant treatment of patients with multidrug-resistant AB pneumonia can improve the therapeutic effect,alleviate the inflammatory response of the body,and increase the bacterial clearance rate.
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