临床医学工程2024,Vol.31Issue(4) :439-440.DOI:10.3969/j.issn.1674-4659.2024.04.0439

替加环素对多重耐药鲍曼不动杆菌肺炎患者血清炎性因子水平的影响

Impact of Tigecycline on Levels of Serum Inflammatory Factors of Patients with Multidrug-Resistant Acinetobacter Bau-mannii Pneumonia

崔宝月 李震 孙源彬 范娟
临床医学工程2024,Vol.31Issue(4) :439-440.DOI:10.3969/j.issn.1674-4659.2024.04.0439

替加环素对多重耐药鲍曼不动杆菌肺炎患者血清炎性因子水平的影响

Impact of Tigecycline on Levels of Serum Inflammatory Factors of Patients with Multidrug-Resistant Acinetobacter Bau-mannii Pneumonia

崔宝月 1李震 2孙源彬 3范娟4
扫码查看

作者信息

  • 1. 南阳市第二人民医院临床药学科,河南南阳 473000
  • 2. 南阳市第二人民医院呼吸内科,河南南阳 473000
  • 3. 南阳市第二人民医院微生物室,河南南阳 473000
  • 4. 南阳市第二人民医院院感染办,河南南阳 473000
  • 折叠

摘要

目的 探讨替加环素辅助治疗多重耐药鲍曼不动杆菌(AB)肺炎患者的临床效果.方法 112例多重耐药AB肺炎患者随机分为两组,对照组给予头孢哌酮舒巴坦治疗,观察组在对照组基础上给予替加环素治疗,比较两组的治疗效果.结果 治疗后,观察组的总有效率、细菌清除率均高于对照组,WBC、CRP、PCT水平均低于对照组(P<0.05).两组的不良反应发生率比较,差异无统计学意义(P>0.05).结论 替加环素辅助治疗多重耐药AB肺炎患者可提高疗效,减轻机体炎性反应,提高细菌清除率.

Abstract

Objective To explore the clinical effect of tigecycline in the adjuvant treatment of patients with multidrug-resistant Acinetobacter Baumannii(AB)pneumonia.Methods 112 patients with multidrug-resistant AB pneumonia were randomly divided into two groups.The control group was treated with cefoperazone sulbactam,and the observation group was treated with tigecycline on the basis of the control group.The therapeutic effects of the two groups were compared.Results After treatment,the total effective rate and bacterial clearance rate of the observation group were higher than those of the control group,and the levels of WBC,CRP,and PCT were lower than those of the control group(P<0.05).No significant difference was found in the incidence of adverse reactions between the two groups(P>0.05).Conclusions Tigecycline in the adjuvant treatment of patients with multidrug-resistant AB pneumonia can improve the therapeutic effect,alleviate the inflammatory response of the body,and increase the bacterial clearance rate.

关键词

多重耐药鲍曼不动杆菌肺炎/替加环素/头孢哌酮舒巴坦/炎性因子

Key words

Multidrug-resistant Acinetobacter Baumannii pneumonia/Tigecycline/Cefoperazone sulbactam/Inflammatory factor

引用本文复制引用

出版年

2024
临床医学工程
国家医疗保健器具工程技术研究中心

临床医学工程

影响因子:0.193
ISSN:1674-4659
参考文献量7
段落导航相关论文