Clinical Effect of Lumbar Cistern Drainage Combined with Intrathecal Injection of Vancomycin in the Treatment of In-tracranial Infection After Craniotomy
Objective To explore the clinical effect of lumbar cistern drainage combined with intrathecal injection of vancomycin in the treatment of intracranial infection after craniotomy.Methods Eighty patients with intracranial infection after craniotomy admitted to our hospital from January 2017 to January 2023 were selected and randomly divided into two groups,with 40 cases in each group.The control group was treated with intravenous infusion of vancomycin hydrochloride,while the observation group was treated with lumbar cistern drainage combined with intrathecal injection of vancomycin.The treatment effect,intracranial pressure,and cerebrospinal fluid related indicators were compared between the two groups.Results The total effective rate of the observation group was 95.00％,significantly higher than 77.50％of the control group(P＜0.05).After treatment,the intracranial pressure,and the levels of white blood cell count and protein in the cerebrospinal fluid of the observation group were significantly lower than those of the control group,while the glucose level in the cerebrospinal fluid was significantly higher than that of the control group(P＜0.05).Conclusions Lumbar cistern drainage combined with intrathecal injection of vancomycin in the treatment of intracranial infection after craniotomy has a significant effect,which can obviously reduce intracranial pressure and improve cerebrospinal fluid indicators of patients.
Lumbar cistern drainageIntrathecal injection of vancomycinIntracranial infection after craniotomy
万方数据
维普
