首页|血清糖化血红蛋白、C肽及空腹血糖联合检测对2型糖尿病肾病的诊断价值

血清糖化血红蛋白、C肽及空腹血糖联合检测对2型糖尿病肾病的诊断价值

扫码查看
目的 探讨血清糖化血红蛋白(HbAlc)、C肽、空腹血糖(FBG)联合检测诊断2型糖尿病肾病的价值.方法 选取2021年5月至2023年6月我院收治的90例2型糖尿病患者,根据是否发生糖尿病肾病分为糖尿病肾病组(32例)和单纯糖尿病组(58例);另选取40例健康者作为对照组.比较三组入院时的血清HbAlc、C肽、FBG水平.分析血清HbAlc、C肽、FBG单独及联合检测对糖尿病肾病的诊断效能.结果 糖尿病肾病组、单纯糖尿病组、对照组的血清HbAlc、FBG水平依次降低,血清C肽水平依次升高(P<0.05).血清HbAlc、C肽及FBG联合检测诊断2型糖尿病肾病的AUC为0.893,高于各指标单独检测(P<0.05).结论 2型糖尿病肾病患者的血清HbAlc、FBG水平异常升高,血清C肽水平异常降低;血清HbAlc、C肽、FBG三项指标联合检测对2型糖尿病肾病的诊断价值较高.
Diagnostic Value of Combined Detection of Serum Glycosylated Hemoglobin,C-Peptide and Fasting Blood Glucose in Type 2 Diabetes Nephropathy
Objective To explore the value of combined detection of serum glycosylated hemoglobin(HbAlc),C-peptide and fasting blood glucose(FBG)in the diagnosis of type 2 diabetes nephropathy.Methods 90 patients with type 2 diabetes admitted to our hospital from May 2021 to June 2023 were selected and divided into the diabetes nephropathy group(32 cases)and the simple diabetes group(58 cases)according to whether diabetes nephropathy occurred;Another 40 healthy individuals during the same period were selected as the control group.The levels of serum HbAlc,C-peptide,and FBG at admission were compared among three groups.The diagnostic efficiencies of single detection and combined detection of serum HbAlc,C-peptide and FBG for diabetes nephropathy were analyzed.Results The levels of serum HbAlc and FBG in the diabetes nephropathy group,the simple diabetes group and the control group decreased in turn,and the level of serum C-peptide increased in tum(P<0.05).The A UC of combined detection of serum HbAlc,C-peptide and FBG in the diagnosis of type 2 diabetes nephropathy was 0.893,higher than that of single detection of each index(P<0.05).Conclusions The levels of serum HbAlc and FBG in patients with type 2 diabetes nephropathy increase abnormally,and the level of serum C-peptide decreases abnormally;The combined detection of serum HbAlc,C-peptide and FBG has high diagnostic value for type 2 diabetes nephropathy.

Glycosylated hemoglobinC-peptideFasting blood glucoseType 2 diabetes nephropathyDiagnostic value

郑亚杰、魏晓霞

展开 >

郑州新华医院检验科,河南郑州 452370

糖化血红蛋白 C肽 空腹血糖 2型糖尿病肾病 诊断价值

2024

临床医学工程
国家医疗保健器具工程技术研究中心

临床医学工程

影响因子:0.193
ISSN:1674-4659
年,卷(期):2024.31(4)
  • 10