首页|血清CEA、CA125及CA199水平联合检测在肺癌诊断中的价值研究

血清CEA、CA125及CA199水平联合检测在肺癌诊断中的价值研究

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目的 分析癌胚抗原(CEA)、糖类抗原125(CA125)及糖类抗原199(CA199)水平联合检测在肺癌诊断中的价值.方法 选取60例肺癌患者为肺癌组,60例良性肺部病变患者为良性组,60例健康者为对照组,比较三组的血清CEA、CA125及CA199水平,分析CEA、CA125、CA199单一与联合检测诊断肺癌的价值.结果 肺癌组的CEA、CA199、CA125水平均高于对照组和良性组,而良性组的各指标水平均高于对照组(P<0.05).CEA、CA125、CA199联合检测诊断肺癌的AUC、敏感度与特异性均高于单一指标检测.结论 肺癌患者的CEA、CA125及CA199水平均异常升高,联合检测可提高诊断效能.
Study on the Value of Combined Detection of Serum CEA,CA125 and CA199 Levels in the Diagnosis of Lung Cancer
Objective To analyze the value of combined detection of carcinoembryonic antigen(CEA),carbohydrate antigen 125(CA125)and carbohydrate antigen 199(CA199)levels in the diagnosis of lung cancer.Methods 60 patients with lung cancer were selected as the lung cancer group,60 patients with benign lung lesions were selected as the benign group,and 60 healthy individuals were selected as the control group.The levels of serum CEA,CA125 and CA199 among the three groups were compared,and the value of single and combined detection of CEA,CA125 and CA199 in the diagnosis of lung cancer was analyzed.Results The levels of CEA,CA199,and CA125 in the lung cancer group were higher than those in the control group and benign group,and the levels of above indicators in the benign group were higher than those in the control group(P<0.05).The combined detection of CEA,CA125,and CA199 in the diagnosis of lung cancer had higherA UC,sensitivity,and specificity than single index detection.Conclusions The levels of CEA,CA125 and CA199 in lung cancer patients are abnormally elevated,and combined detection can improve diagnostic efficiency.

Lung cancerCarcinoembryonic antigenCarbohydrate antigen 125Carbohydrate antigen 199Diagnosis

马莹辉、潘永平、金佳培

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洛阳市第三人民医院检验科,河南洛阳 471000

洛阳市第一人民医院检验科,河南洛阳 471000

肺癌 癌胚抗原 糖类抗原125 糖类抗原199 诊断

2024

临床医学工程
国家医疗保健器具工程技术研究中心

临床医学工程

影响因子:0.193
ISSN:1674-4659
年,卷(期):2024.31(4)
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