Study on the Correlation between PT,APTT,D-Dimer and Blood Glucose Levels in Patients with Gestational Diabetes Mellitus
Objective To analyze the correlation between prothrombin time(PT),activated partial thromboplastin time(APTT),D-Dimer and blood glucose levels in patients with gestational diabetes mellitus.Methods 60 patients with gestational diabetes mellitus from October 2020 to October 2022 were selected as patient group,and 60 healthy pregnant women with physical examination at the same time were selected as healthy group.The coagulation function indicators and blood glucose levels were detected,and the correlation between coagulation function indicators and blood glucose levels of patients with gestational diabetes mellitus was analyzed.The pregnancy outcome was compared between the two groups.Results The D-Dimer,FPG and 2hPG levels of the patient group were higher than those of the healthy group,and the PT and APTT were shorter than those of the healthy group(P＜0.05).Among patients with gestational diabetes mellitus,PT and APTT were negatively correlated with FPG and 2hPG(r=-0.364,-0.563,-0.426,-0.631,P＜0.05),while D-Dimer was positively correlated with FPG and 2hPG(r=0.341,0.482,P＜0.05).The incidence of adverse pregnancy outcomes in the patient group was higher than that in the healthy group(P＜0.05).Conclusions The coagulation function indicators in patients with gestational diabetes mellitus are significantly different from those of healthy pregnant women.The blood glucose level is closely correlated with the coagulation function.High blood coagulation status tends to increase the risk of adverse pregnancy outcomes.
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