Predictive Value of Serum NSE,CEA,and CA125 Detection for Short-Term Efficacy after 125I Implantation in Patients with Lung Cancer
Objective To explore the predictive value of serum neuron specific enolase(NSE),carcinoembryonic antigen(CEA)and carbohydrate antigen 125(CA125)for short-term efficacy after 125I implantation in patients with lung cancer.Methods 86 patients with lung cancer admitted to our hospital from April 2024 to December 2022 were selected and given 125I implantation.The serum NSE,CEA and CA125 levels before and after treatment were compared,and the efficacy was evaluated.The serum NSE,CEA and CA125 levels of patients with different efficacy were compared,and Logistic regression analysis was used to analyze the multiple factors that affected efficacy.Results After treatment,the serum NSE,CEA,and CA125 levels of patients were lower than those before treatment(P＜0.05).The serum NSE,CEA,and CA125 levels of the effective group were lower than those of the ineffective group(P＜0.05).NSE,CEA and CA125 were independent risk factors for ineffective 125I implantation in patients with lung cancer(OR＞1,P＜0.05).Conclusions Serum NSE,CEA and CA1 25 levels are influencing factors for the effiicacy of 125I implantation in the treatment of patients with lung cancer,which can be used for short-term efficacy prediction.
Carcinoembryonic antigenCarbohydrate antigenLung cancer
国家科技期刊平台
NSTL
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