Observation on the Effect of Aspirin Enteric-Coated Tablets Combined with Methylprednisolone Sodium Succinate in the Treatment of Children with Allergic Purpura
Objective To observe the effect of aspirin enteric-coated tablets combined with methylprednisolone sodium succinate in the treatment of children with allergic purpura.Methods 92 children with allergic purpura admitted to our hospital from April 2022 to April 2023 were randomly divided into two groups equally.Both groups received basic treatment after admission,the control group received oral aspirin enteric-coated tablets,and the observation group received injection of methylprednisolone sodium succinate.Both groups maintained treatment for 1 week.The clinical efficacy,symptom resolution time,inflammatory reactions,and adverse reactions were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group,and the resolution time of rash,joint swelling and pain,bloody stool,and kidney injury were shorter than those of the control group(P＜0.05).After treatment,the IL-6,TNF-α and hs-CRP levels of the observation group were lower than those of the control group(P＜0.05).No statistical difference was found in the incidence of adverse reactions between the two groups(P＞0.05).Conclusions Aspirin enteric-coated tablets combined with methylprednisolone sodium succinate in the treatment of children with allergic purpura has significant clinical efficacy,which can shorten the symptom resolution time,reduce the inflammatory reactions,and will not increase adverse drug reactions,with higher safety.
Children with allergic purpuraAspirin enteric-coated tabletsMethylprednisolone sodium succinateEffect
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