QCT Bone Mineral Density Measurement in Evaluation of Osteoporosis and Prognosis of Elderly Diabetic Patients Treated with SGLT-2 Inhibitors
Objective To explore the application value of bone mineral density(BMD)detected by quantitative CT(QCT)in evaluating osteoporosis and prognosis of elderly diabetic patients treated with SGLT-2 inhibitors.Methods A total of 100 elderly diabetic patients admitted to our hospital from January 2018 to June 2022 were selected and divided into the SGLT-2 group and non-SGLT-2 group according to whether SGLT-2 inhibitors were used.The BMD was compared between the two groups,and the BMD was compared between patients with different prognosis in SGLT-2 group.Results The comparison of L1,L2,L3 and L1～L3 BMD before and after treatment showed no significant difference in SGLT-2 group(P＞0.05).No significant difference was found in BMD of L1,L2,L3 and L1～L3 after treatment between the SGLT-2 group and the non-SGLT-2 group(P＞0.05).In SGLT-2 group,the BMD of L1,L2,L3 and L1～L3 in patients with poor prognosis were significantly lower than those in patients with good prognosis(P＜0.05).Conclusions The impact of SCLT-2 inhibitors on BMD in elderly patients with diabetes may be mild.The use of QCT to measure BMD can early detect the potential risk of osteoporosis and fracture of patients,and can be used for prognostic evaluation.
国家科技期刊平台
NSTL
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