依达拉奉右莰醇治疗急性脑梗死的临床效果观察
Observation on the Clinical Effect of Edaravone Dexborneol in the Treatment of Acute Cerebral Infarction
李朝飞 1李朝红 2李建甫 3李领召4
作者信息
- 1. 禹州市中医院病案科,河南禹州 461670
- 2. 禹州市中医院老年病科,河南禹州 461670
- 3. 禹州市中医院重症医学科,河南禹州 461670
- 4. 禹州市中医院脑病科,河南禹州 461670
- 折叠
摘要
目的 探讨依达拉奉右莰醇治疗急性脑梗死(ACI)的临床效果.方法 100例ACI患者随机分为两组各50例.在常规治疗基础上,参照组给予rtPA溶栓治疗,研究组给予rtPA溶栓联合依达拉奉右莰醇注射液治疗.比较两组的治疗效果、神经功能、日常生活能力以及神经因子水平.结果 研究组的治疗总有效率为94.00％,高于参照组的80.00％(P＜0.05).治疗后,研究组的NIHSS评分、mRS评分均低于参照组,IGF-1水平高于参照组,NSE、Hcy水平均低于参照组(P＜0.05).、结论依达拉奉右莰醇治疗急性脑梗死的效果确切,可明显改善患者的神经因子水平,促进患者的神经功能恢复,提高患者的日常生活能力.
Abstract
Objective To explore the clinical effect of edaravone dexborneol in the treatment of acute cerebral infarction(ACI).Methods A total of 100 patients with ACI were randomly divided into two groups,with 50 cases in each group.On the basis of routine therapy,the reference group was treated with rtPA thrombolysis,and the study group was treated with rtPA thrombolysis combined with edaravone dexborneol for injection.The therapeutic effect,neurological function,daily living ability and nerve factor levels were compared between the two groups.Results The total effective rate of treatment in the study group was 94.00％,higher than 80.00％in the reference group(P＜0.05).After treatment,the NIHSS score and mRS score in the study group were lower than those in the reference group,the IGF-1 level was higher than that in the reference group,and the NSE and Hcy levels were lower than those in the reference group(P＜0.05).Conclusions Edaravone dexborneol in the treatment of acute cerebral infarction has exact effect,which can obviously improve the levels of nerve factors,promote the recovery of neurological function and improve the daily living ability of patients.
关键词
急性脑梗死/依达拉奉右莰醇/神经功能/日常生活能力/神经因子Key words
Acute cerebral infarction/Edaravone dexborneol/Neurological function/Daily living ability/Nerve factor引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据