左甲状腺素钠治疗对妊娠合并甲状腺功能减退患者甲状腺功能指标及母婴结局的影响
Impact of Levothyroxine Sodium Treatment on Thyroid Function Indicators and Maternal and Infant Outcomes of Pregnan-cy Patients with Hypothyroidism
于海微 1林锦芬 1黄团明1
作者信息
- 1. 厦门市中医院妇产科,福建厦门 361009
- 折叠
摘要
目的 探讨左甲状腺素钠治疗妊娠合并甲状腺功能减退患者的效果.方法 378例妊娠合并甲状腺功能减退患者随机分为两组,对照组采用甲状腺片治疗,观察组采用左甲状腺素钠治疗,对比两组的临床疗效.结果 治疗后,观察组的FT4、FT3水平均高于对照组,TSH水平、不良母婴结局发生率均低于对照组(P＜0.05).两组的不良反应发生率对比,差异无统计学意义(P＞0.05).结论 左甲状腺素钠治疗妊娠合并甲状腺功能减退患者可有效改善其甲状腺功能与母婴结局.
Abstract
Objective To explore the effect of levothyroxine sodium in the treatment of pregnancy patients with hypothyroidism.Methods 378 pregnancy patients with hypothyroidism were randomly divided into two groups.The control group was treated with thyroid tablets,and the observation group was treated with levothyroxine sodium.The clinical effiicacy was compared between the two groups.Results After treatment,the levels of FT4 and FT3 in the observation group were higher than those in the control group,and the TSH level and the incidence of adverse maternal and infant outcomes were lower than those in the control group(P＜0.05).No significant difference was found in the incidence of adverse reactions between the two groups(P＞0.05).Conclusions Levothyroxine sodium in the treatment of pregnancy patients with hypothyroidism can effectively improve their thyroid function and maternal and infant outcomes.
关键词
妊娠/甲状腺功能减退/左甲状腺素钠/甲状腺功能/母婴结局/不良反应Key words
Pregnancy/Hypothyroidism/Levothyroxine sodium/Thyroid function/Maternal and infant outcomes/Adverse reaction引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据