布地奈德雾化吸入结合阿奇霉素序贯疗法对难治性支原体肺炎患儿肺功能、炎症指标水平的影响
Impact of Budesonide Aerosol Inhalation Combined with Azithromycin Sequential Therapy on Pulmonary Function and Lev-els of Inflammatory Indicators of Children with Refractory Mycoplasma Pneumonia
苏海芳 1彭其文1
作者信息
- 1. 福建省仙游县总医院儿科,福建莆田 351200
- 折叠
摘要
目的 探讨布地奈德雾化吸入结合阿奇霉素序贯疗法治疗支原体肺炎的效果.方法 78例难治性支原体肺炎患儿随机分为两组,对照组给予阿奇霉素序贯疗法,观察组在对照组基础上给予布地奈德雾化吸入治疗,比较两组的疗效、肺功能及炎症指标.结果 治疗后,观察组的总有效率以及FEV1、FVC、PEF水平均高于对照组,TNF-α、IFN-γ、IL-2、IL-6水平均低于对照组(P＜0.05).结论 布地奈德雾化吸入结合阿奇霉素序贯疗法治疗难治性支原体肺炎能明显改善患儿的肺功能及炎症指标.
Abstract
Objective To explore the effect of budesonide aerosol inhalation combined with azithromycin sequential therapy in the treatment of refractory mycoplasma pneumonia.Methods 78 children with refractory mycoplasma pneumonia were randomly divided into two groups.The control group was treated with azithromycin sequential therapy,and the observation group was treated with budesonide aerosol inhalation on the basis of the control group.The efficacy,pulmonary function and inflammation indicators were compared between the two groups.Results After treatment,the total effective rate and the levels of FEV1,FVC and PEF in the observation group were higher than those in the control group,and the levels of TNF-α,IFN-γ,IL-2 and IL-6 were lower than those in the control group(P＜0.05).Conclusions Budesonide aerosol inhalation combined with azithromycin sequential therapy in the treatment of refractory mycoplasma pneumonia can obviously improve the pulmonary function and inflammatory indicators of children.
关键词
难治性支原体肺炎/阿奇霉素序贯疗法/布地奈德/肺功能Key words
Refractory mycoplasma pneumonia/Azithromycin sequential therapy/Budesonide/Pulmonary function引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据