首页|早期肠内营养支持对脓毒症患者营养状态、炎性反应及肠道菌群的影响

早期肠内营养支持对脓毒症患者营养状态、炎性反应及肠道菌群的影响

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目的 分析早期肠内营养支持在脓毒症患者治疗中的应用效果.方法 20例脓毒症患者均给予常规治疗+早期肠内营养支持治疗,比较治疗前后的营养状态、炎性反应以及肠道菌群丰度.结果 治疗后,脓毒症患者的HGB、Alb、TRF水平均高于治疗前,IL-6、TNF-α、PCT水平均低于治疗前,厌氧胞杆菌属丰度高于治疗前,梭菌属、考拉杆菌属、颤杆菌属、另枝菌属丰度均低于治疗前(P<0.05).结论 早期肠内营养支持可改善脓毒症患者的营养状态与炎性反应状态,调整肠道菌群丰度.
Impact of Early Enteral Nutrition Support on Nutritional Status,Inflammatory Response and Intestinal Flora of Patients with Sepsis
Objective To analyze the application effect of early enteral nutrition support in the treatment of patients with sepsis.Methods 20 patients with sepsis were given routine treatment+early enteral nutrition support treatment,and the nutritional status,inflammatory response and intestinal flora abundance before and after treatment were compared.Results After treatment,the levels of HGB,Alb and TRF of patients with sepsis were higher than those before treatment,the levels of IL-6,TNF-α and PCT were lower than those before treatment,the abundance of Anaerobes was higher than that before treatment,and the abundances of Clostridium,Coronobacter,Oscillibacter and Arbuscular were lower than those before treatment(P<0.05).Conclusions Early enteral nutrition support can improve the nutritional status and inflammatory response status of patients with sepsis,and adjust the abundance of intestinal flora.

Early enteral nutrition supportSepsisNutritional statusInflammatory responseIntestinal flora

王建峰、杨楠楠、刘宁宁、邢云飞、付刚

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河南理工大学第一附属医院重症医学科,河南焦作 454000

河南理工大学第一附属医院病理科,河南焦作 454000

早期肠内营养支持 脓毒症 营养状态 炎性反应 肠道菌群

2024

临床医学工程
国家医疗保健器具工程技术研究中心

临床医学工程

影响因子:0.193
ISSN:1674-4659
年,卷(期):2024.31(6)
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