首页|尿液细菌培养阳性菌群分布及其与PCT、CRP水平的关系

尿液细菌培养阳性菌群分布及其与PCT、CRP水平的关系

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目的 探讨尿液培养阳性菌株菌群的分布特点及其与PCT、CRP水平的关系.方法 选取尿液培养阳性患者648例,记录病原菌检出情况.选取同期健康体检者45例,比较阳性患者和健康者的PCT、CRP水平.分析革兰阳性菌和阴性菌检出的影响因素.结果 648例尿液培养阳性患者共分离出683株细菌;革兰阴性菌536株,排在前三位的分别为大肠埃希菌、肺炎克雷伯菌和铜绿假单胞菌;革兰阳性菌147株,其中屎肠球菌占比最高.革兰阳性菌患者的PCT、CRP水平高于健康者(P<0.05),革兰阴性菌患者的PCT、CRP水平高于革兰阳性菌患者(P<0.05).Logistic回归分析结果显示,PCT、CRP对革兰阳性菌和阴性菌的检出有影响(P均<0.05).结论 大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌及屎肠球菌是尿液培养阳性患者的主要致病菌,检测PCT、CRP水平可初步鉴别革兰阴性菌和革兰阳性菌引起的尿液感染.
Distribution of Positive Bacteria in Urine Bacterial Culture and Its Relationships with PCT and CRP Levels
Objective To explore the distribution characteristics of bacterial flora in urine culture positive strains and its relationships with PCT and CRP levels.Methods A total of 648 patients with positive urine culture were selected,and the detection of pathogenic bacteria was recorded.45 healthy subjects were selected during the same period,and the levels of PCT and CRP were compared between positive patients and healthy subjects.The influencing factors of the detection of Gram-positive bacteria and Gram-negative bacteria were analyzed.Results A total of 683 strains of bacteria were isolated from 648 patients with positive urine culture;There were 536 strains of Gram-negative bacteria,and the top three were Escherichia coli,Klebsiella pneumoniae and Pseudomonas aeruginosa;There were 147 strains of Gram-positive bacteria,of which Enterococcus faecium accounted for the highest proportion.The levels of PCT and CRP in patients with Gram-positive bacteria were higher than those in healthy subjects(P<0.05),and the levels of PCT and CRP in patients with Gram-negative bacteria were higher than those in patients with Gram-positive bacteria(P<0.05).Logistic regression analysis showed that PCT and CRP had effects on the detection of Gram-positive and Gram-negative bacteria(P<0.05).Conclusions Escherichia coli,Klebsiella pneumoniae,Pseudomonas aeruginosa and Enterococcus faecium are the main pathogenic bacteria in patients with positive urine culture.Detection of PCT and CRP levels can preliminarily identify urine infections caused by Gram-negative bacteria and Gram-positive bacteria.

Positive urine bacterial cultureDistribution of bacterial floraPCTCRP

邢利明、詹江辉、赵长波

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新乡市第二人民医院检验科,河南新乡 453000

尿液细菌培养阳性 菌群分布 PCT CRP

2024

临床医学工程
国家医疗保健器具工程技术研究中心

临床医学工程

影响因子:0.193
ISSN:1674-4659
年,卷(期):2024.31(6)
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