Relationships of Serum CRP,LPS and AMY with the Disease Severity and Poor Prognosis of Patients with Acute Pancreatitis
Objective To explore the relationships of serum CRP,LPS and AMY with the disease severity and poor prognosis of patients with acute pancreatitis.Methods 100 patients with acute pancreatitis were selected as the acute pancreatitis group,100 healthy people were selected as the control group,and the levels of CRP,LPS and AMY were compared between the two groups.The levels of CRP,LPS and AMY in patients with different disease severity and different prognosis were compared,and the risk factors of poor prognosis were analyzed.Results The levels of serum CRP,LPS and AMY in the acute pancreatitis group were higher than those in the control group(P＜0.05).The serum CRP level of patients with severe acute pancreatitis was higher than that of patients with mild acute pancreatitis,and the serum CRP,LPS and AMY levels of patients with poor prognosis were higher than those of patients with good prognosis(P＜0.05).Logistic regression analysis showed that CRP,LPS and AMY were independent risk factors of poor prognosis in patients with acute pancreatitis(OR＞1,P＜0.05).Conclusions The levels of serum CRP,LPS and AMY in patients with acute pancreatitis elevate abnormally,which can be used for prognosis assessment,and CRP can be used to evaluate the severity of the disease.
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