血清CRP、LPS、AMY与急性胰腺炎患者病情严重程度及预后不良的关系
Relationships of Serum CRP,LPS and AMY with the Disease Severity and Poor Prognosis of Patients with Acute Pancreatitis
曹春爽 1郑雄辉2
作者信息
- 1. 泉州市德化县医院检验科,福建泉州 362500
- 2. 泉州市德化县医院放射科,福建泉州 362500
- 折叠
摘要
目的 探讨CRP、LPS、AMY与急性胰腺炎患者病情严重程度与预后不良的关系.方法 选取100例急性胰腺炎患者为急性胰腺炎组,100例健康者为对照组,比较两组的CRP、LPS、AMY水平.比较不同病情严重程度、不同预后患者的CRP、LPS、AMY水平,分析预后不良的危险因素.结果 急性胰腺炎组的血清CRP、LPS、AMY水平均高于对照组(P＜0.05).重型急性胰腺炎患者的血清CRP水平高于轻型急性胰腺炎患者,预后不良患者的血清CRP、LPS、AMY水平均高于预后良好患者(P＜0.05).Logistic回归分析显示,CRP、LPS、AMY均为急性胰腺炎患者预后不良的独立危险因素(OR＞1,P＜0.05).结论 急性胰腺炎患者的血清CRP、LPS、AMY水平异常升高,可用于预后判断,其中CRP可用于病情严重程度评估.
Abstract
Objective To explore the relationships of serum CRP,LPS and AMY with the disease severity and poor prognosis of patients with acute pancreatitis.Methods 100 patients with acute pancreatitis were selected as the acute pancreatitis group,100 healthy people were selected as the control group,and the levels of CRP,LPS and AMY were compared between the two groups.The levels of CRP,LPS and AMY in patients with different disease severity and different prognosis were compared,and the risk factors of poor prognosis were analyzed.Results The levels of serum CRP,LPS and AMY in the acute pancreatitis group were higher than those in the control group(P＜0.05).The serum CRP level of patients with severe acute pancreatitis was higher than that of patients with mild acute pancreatitis,and the serum CRP,LPS and AMY levels of patients with poor prognosis were higher than those of patients with good prognosis(P＜0.05).Logistic regression analysis showed that CRP,LPS and AMY were independent risk factors of poor prognosis in patients with acute pancreatitis(OR＞1,P＜0.05).Conclusions The levels of serum CRP,LPS and AMY in patients with acute pancreatitis elevate abnormally,which can be used for prognosis assessment,and CRP can be used to evaluate the severity of the disease.
关键词
急性胰腺炎/CRP/LPS/AMY/病情严重程度/预后Key words
Acute pancreatitis/CRP/LPS/AMY/Disease severity/Prognosis引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据