Quantitative Evaluation Value of DTI Combined with DWI for Early Ischemic Penumbra of Acute Cerebral Infarction
Objective To analyze the quantitative evaluation value of magnetic resonance diffusion tensor imaging(DTI)combined with diffusion weighted imaging(DWI)for early ischemic penumbra(IP)of acute cerebral infarction(ACI).Methods 80 ACI patients were selected and given magnetic resonance DTI and DWI examination.According to the onset time,the patients were divided into hyperacute group(<6 h,n=24),acute group(6～24 h,n=26)and subacute group(24～72 h,n=30).The DCavg,ADC and FA values of infarct center area,IP area and contralateral mirror area in ACI patients were compared,and the rDCavg,rADC and rFA values of IP area in ACI patients at different onset stages were compared.Results The comparison of DCavg,ADC,and FA values in different regions of ACI patients showed that the infarct center area<IP area<contralateral mirror area(P<0.05).The comparison of rDCavg,rADC,and rFA values in the IP area of ACI patients at different onset stages showed that hyperacute group>acute group>subacute group(P<0.05).Conclusions The relevant quantitative parameters of DTI combined with DWI have higher evaluation value for early IP of ACI,which can be applied clinically for reference.
Acute cerebral infarctionIschemic penumbraDiffusion tensor imagingDiffusion weighted imagingQuantitative parameterEvaluation value
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