Effect of Different Laparoscopic Liver Blood Flow Occlusion in the Treatment of Liver Cancer and the Impact on the Intestinal Microbiota of Patients
Objective To explore the effect of laparoscopic liver blood flow occlusion in the treatment of liver cancer and the impact on the intestinal microbiota of patients.Methods 123 patients with liver cancer undergoing laparoscopic right hemihepatectomy in our hospital were selected and divided into study group(Glisson extrathecal blood flow occlusion of right hepatic pedicle)and control group(Pringle blood flow occlusion)according to different liver blood flow occlusion during surgery.The perioperative indicators,inflammatory indicators,liver function indicators,intestinal microbiota,and prognosis were compared between the two groups.Results The surgical time and hospitalization time of the study group were shorter than those of the control group,and the incidence of complications was lower than that of the control group(P<0.05).After surgery,the IL-6,hs-CRP,ALT and AST levels of the study group were lower than those of the control group(P<0.05).After surgery,the intestinal probiotics of the study group were higher than those of the control group,while the intestinal pathogens were lower than those of the control group(P<0.05).After 1 year,no statistical difference was found in the survival rate between the two groups(P>0.05).Conclusions Glisson extrathecal blood flow occlusion of right hepatic pedicle during laparoscopic right hemihepatectomy has better effect on patients with liver cancer,which can reduce the inflammatory reactions and liver function damage,promote patients'recovery,and is worthy of clinical promotion and application.
国家科技期刊平台
NSTL
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