Impact of Skull Repair Surgery at Different Timing on Cerebral Hemodynamic Indicators and Prognosis in Patients with Craniocerebral Injury
Objective To explore the impact of skull repair surgery at different timing on cerebral hemodynamics indicators and prognosis in patients with craniocerebral injury.Methods 60 patients with craniocerebral injury admitted to our hospital from October 2021 to October 2022 were randomly divided into reference group(n=30)and observation group(n=30).Both groups were given decompressive craniectomy,the reference group underwent skull repair at 3-6 months after surgery,and the observation group underwent skull repair within 3 months after surgery.The cerebral hemodynamic indicators and prognosis were compared between the two groups.Results 1 week after surgery,the serum myelin basic protein(MBP),calcium binding protein β(S-100β)and neuron-specific enolase(NSE)levels of the observation group were lower than those of the reference group(P<0.05).After 3 months of follow-up,the prognosis of the observation group was better than that of the reference group(P<0.05).Conclusions Early skull repair surgery after decompressive craniectomy can significantly reduce the serum MBP,S-100βand NSE levels of patients with craniocerebral injury,with more ideal prognosis of patients.
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