首页|替罗非班联合酒石酸美托洛尔片治疗急性心肌梗死患者的效果观察

替罗非班联合酒石酸美托洛尔片治疗急性心肌梗死患者的效果观察

扫码查看
目的 观察替罗非班联合酒石酸美托洛尔片治疗急性心肌梗死患者的效果.方法 选择 2021 年 4 月至 2023 年 4 月我院收治的 114 例急性心肌梗死患者随机分为对照组(57 例)和观察组(57 例).对照组口服酒石酸美托洛尔片治疗,观察组在对照组基础上采用替罗非班治疗.比较两组的临床疗效、心功能指标和血清炎性因子水平.结果 观察组总有效率为 96.49%,高于对照组的 84.21%(P<0.05).治疗后,观察组左心室射血分数(LVEF)、心输血量(CO)均高于对照组,左心室舒张末期内径(LVEDD)、心肌肌钙蛋白I(cTnI)、肌酸激酶同工酶(CK-MB)、γ干扰素(IFN-γ)水平均低于对照组(P<0.05).结论 替罗非班联合酒石酸美托洛尔片治疗急性心肌梗死患者的效果明显,可显著改善其心功能指标和血清炎性因子水平.
Observation on the Effect of Tirofiban Combined with Metoprolol Tartrate Tablets in the Treatment of Patients with Acute Myocardial Infarction
Objective To observe the effect of tirofiban combined with metoprolol tartrate tablets in the treatment of patients with acute myocardial infarction.Methods 114 patients with acute myocardial infarction admitted to our hospital from April 2021 to April 2023 were selected and randomly divided into control group(57 cases)and observation group(57 cases).The control group was treated with oral metoprolol tartrate tablets,while the observation group was treated with tirofiban on the basis of the control group.The clinical efficacy,cardiac function indicators and serum inflammatory factor levels of the two groups were compared.Results The total effective rate of the observation group was 96.49%,higher than 84.21%of the control group(P<0.05).After treatment,the LVEF and CO of the observation group were higher than those of the control group,and the LVEDD,cTnI,CK-MB and IFN-γ were lower than those of the control group(P<0.05).Conclusions Tirofiban combined with metoprolol tartrate tablets has significant effect in the treatment of patients with acute myocardial infarction,which can significantly improve the cardiac function indicators and serum inflammatory factor levels of patients.

TirofibanMetoprolol tartrate tabletAcute myocardial infarctionCardiac function

付艳华、余春华

展开 >

郑州大学第五附属医院老年医学科,河南郑州 450052

替罗非班 酒石酸美托洛尔片 急性心肌梗死 心功能

2024

临床医学工程
国家医疗保健器具工程技术研究中心

临床医学工程

影响因子:0.193
ISSN:1674-4659
年,卷(期):2024.31(7)