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慢性肾衰竭患者发生脑血管疾病的危险因素分析

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目的 分析慢性肾衰竭患者(CRF)发生脑血管疾病的危险因素.方法 选取 2021 年 6 月至 2022 年 1 月我院收治的120 例CRF患者,根据有无发生脑血管疾病将其分为发生组(n=49)和未发生组(n=71).统计两组患者一般资料,采用单因素和多因素分析影响CRF患者发生脑血管疾病的危险因素.结果 CRF患者脑血管疾病的发生可能受其年龄、BMI、长期饮酒、合并糖尿病、合并高血脂、肾小球滤过率(GFR)、总同型半胱氨酸(tHcy)水平的影响(P<0.05);多因素Logistic回归分析结果显示,长期饮酒、合并糖尿病、合并高血脂、tHcy水平偏高为影响CRF患者发生脑血管疾病的独立危险因素(OR=2.102、2.377、3.177、4.773,P=0.037、0.036、0.040、0.027).结论 长期饮酒、合并糖尿病、合并高血脂、tHcy水平偏高均为影响CRF患者发生脑血管疾病的独立危险因素,临床应对上述危险因素尽早做好预防干预措施,以减少CRF患者脑血管疾病的发生.
Analysis on Risk Factors for Cerebrovascular Disease in Patients with Chronic Renal Failure
Objective To analyze the risk factors of cerebrovascular disease in patients with chronic renal failure(CRF).Methods 120 CRF patients admitted to our hospital from June 2021 to January 2022 were selected and divided into occurrence group(n=49)and non-occurrence group(n=71)according to whether they had cerebrovascular disease.The general data of the two groups were counted,and the risk factors for cerebrovascular disease in CRF patients were analyzed by univariate and multivariate analysis.Results The occurrence of cerebrovascular disease in CRF patients might be affected by their age,BMI,long-term drinking,diabetes mellitus,hyperlipidemia,glomerular filtration rate(GFR),and total homocysteine(tHcy)level(P<0.05).Multivariate Logistic regression analysis showed that long-term drinking,diabetes mellitus,hyperlipidemia and high tHcy level were independent risk factors for cerebrovascular disease in CRF patients(OR=2.102,2.377,3.177,4.773,P=0.037,0.036,0.040,0.027).Conclusions Long-term drinking,diabetes mellitus,hyperlipidemia,and high tHcy level are independent risk factors for cerebrovascular diseases in CRF patients.Clinical prevention and intervention measures should be taken as soon as possible to reduce the occurrence of cerebrovascular diseases in CRF patients.

Chronic renal failureCerebrovascular diseaseRisk factor

祁孟丽、任东升

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南阳市中心医院肾病内科,河南南阳 473000

慢性肾衰竭 脑血管疾病 危险因素

2024

临床医学工程
国家医疗保健器具工程技术研究中心

临床医学工程

影响因子:0.193
ISSN:1674-4659
年,卷(期):2024.31(7)