Etiological Analysis on Catheter-Related Bloodstream Infection in Single Center Hemodialysis from 2014 to 2022
Objective To analyze the etiological changes of catheter-related bloodstream infection(CRBSI)in patients with maintenance hemodialysis(MHD).Methods 231 patients undergoing MHD in our hospital from January 2014 to December 2022 were selected and divided into CRBSI group(n=197)and non-CRBSI group(n=34)according to CRBSI or none.Results A total of 57 strains of pathogenic bacteria were detected in 197 patients in the CRBSI group,mainly gram-negative bacteria.Staphylococcus aureus had higher resistance rate to penicillin,cefuroxime and oxacillin,Escherichia coli had higher resistance rate to compound sulfamethoxazole and ceftriaxone,and Klebsiella pneumoniae had higher resistance rate to compound sulfamethoxazole and aztreonam.Age≥60 years old,≥2 weeks of catheterization,comorbid chronic diseases,and no history of antimicrobial use within 1 month were independent risk factors for CRBSI(P<0.05).Conclusions MHD patients are at high risk of CRBSI due to advanced age,chronic diseases,long catheterization time,and no recent history of antimicrobial use,and the pathogenic bacteria are mainly gram-negative bacteria.
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