首页|低剂量甲泼尼龙联合布地奈德对小儿重症支原体肺炎的影响

低剂量甲泼尼龙联合布地奈德对小儿重症支原体肺炎的影响

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目的 探讨低剂量甲泼尼龙联合布地奈德治疗小儿重症支原体肺炎的效果.方法 选取我院 2022 年 10 月至 2023 年10 月收治的 98 例重症支原体肺炎患儿,根据用药方案的不同分为两组.对照组 48 例给予布地奈德混悬液雾化吸入,观察组 50例在对照组基础上给予低剂量甲泼尼龙琥珀酸钠治疗.比较两组的临床疗效、症状改善时间和不良反应.结果 治疗后,观察组的总有效率为 96.00%,高于对照组的 79.17%(P<0.05).观察组的退热时间、咳嗽缓解时间、肺部啰音消失时间、胸片恢复正常时间均短于对照组(P<0.05).两组的药物不良反应总发生率比较,差异无统计学意义(P>0.05).结论 低剂量甲泼尼龙联合布地奈德治疗重症支原体肺炎的效果较好,可缓解患儿的症状体征,安全性高.
Impact of Low-Dose Methylprednisolone Combined with Budesonide on Severe Mycoplasma Pneumonia in Children
Objective To explore the effect of low-dose methylprednisolone combined with budesonide in the treatment of severe mycoplasma pneumonia in children.Methods 98 children with severe mycoplasma pneumonia admitted to our hospital from October 2022 to October 2023 were selected and divided into two groups according to different medication regimens.48 cases in the control group were given budesonide suspension for atomization inhalation,and 50 cases in the observation group were given low-dose methylprednisolone sodium succinate on the basis of the control group.The clinical efficacy,symptom improvement time and adverse reactions were compared between the two groups.Results After treatment,the total effective rate of the observation group was 96.00%,higher than 79.17%of the control group(P<0.05).The antipyretic time,cough relief time,lung rale disappearance time and chest X-ray recovery time of the observation group were shorter than those of the control group(P<0.05).No significant difference was found in the total incidence of adverse drug reactions between the two groups(P>0.05).Conclusions Low-dose methylprednisolone combined with budesonide in the treatment of severe mycoplasma pneumonia has good effect and high safety,and can relieve the symptoms and signs of children.

Low-dose methylprednisoloneBudesonideSevere mycoplasma pneumonia

仇冬梅、申飞飞、沈丽媛、吴尤佳

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南通大学附属医院小儿内科,江苏南通 226000

低剂量甲泼尼龙 布地奈德 重症支原体肺炎

江苏省卫生健康委医学科研重点项目

ZD2021004

2024

临床医学工程
国家医疗保健器具工程技术研究中心

临床医学工程

影响因子:0.193
ISSN:1674-4659
年,卷(期):2024.31(8)