首页|低分子肝素治疗妊娠期糖尿病伴孕中期血脂异常孕妇的临床效果

低分子肝素治疗妊娠期糖尿病伴孕中期血脂异常孕妇的临床效果

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目的 探讨低分子肝素治疗妊娠期糖尿病(GDM)伴孕中期血脂异常孕妇的临床效果.方法 选取 2020 年 10 月至2022 年 12 月在我院产检并分娩的 80 例GDM伴孕中期血脂异常孕妇,随机分为两组各 40 例.对照组给予常规治疗,研究组在对照组基础上给予低分子肝素治疗.比较两组的血脂水平、母婴结局.结果 治疗后,两组的HDL水平均显著高于治疗前,LDL、TG、TC水平均显著低于治疗前(P<0.05);且研究组的HDL水平显著高于对照组,LDL、TG、TC水平均显著低于对照组(P<0.05).研究组的不良母婴结局总发生率为 7.50%,显著低于对照组的 25.00%(P<0.05).结论 低分子肝素治疗GDM伴孕中期血脂异常孕妇的效果显著,能够明显改善血脂水平,减少不良母婴结局发生风险.
Clinical Effect of Low Molecular Weight Heparin in the Treatment of Pregnant Women with Gestational Diabetes Mellitus Complicated with Dyslipidemia in the Second Trimester of Pregnancy
Objective To explore the clinical effect of low molecular weight heparin in the treatment of pregnant women with gestational diabetes mellitus(GDM)complicated with dyslipidemia in the second trimester of pregnancy.Methods A total of 80 pregnant women with GDM complicated with dyslipidemia in the second trimester of pregnancy who were examined and delivered in our hospital from October 2020 to December 2022 were selected and randomly divided into two groups,with 40 cases in each group.The control group was given routine treatment,and the study group was treated with low molecular weight heparin on the basis of the control group.The blood lipid levels,and maternal and infant outcomes were compared between the two groups.Results After treatment,the levels of HDL in the two groups were significantly higher than those before treatment,and the levels of LDL,TG and TC were significantly lower than those before treatment(P<0.05);The HDL level in the study group was significantly higher than that in the control group,and the levels of LDL,TG and TC were significantly lower than those in the control group(P<0.05).The total incidence of adverse maternal and infant outcomes in the study group was 7.50%,significantly lower than 25.00%in the control group(P<0.05).Conclusions Low molecular weight heparin in the treatment of pregnant women with GDM complicated with dyslipidemia in the second trimester of pregnancy has significant effect,which can obviously improve the blood lipid levels and reduce the occurrence risk of adverse maternal and infant outcomes.

Gestational diabetes mellitusDyslipidemiaLow molecular weight heparinBlood lipidMaternal and infant outcomes

车盼盼、闫望南

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开封市妇幼保健院 产一科,河南开封 475000

开封市妇幼保健院 妇科,河南开封 475000

妊娠期糖尿病 血脂异常 低分子肝素 血脂 母婴结局

2024

临床医学工程
国家医疗保健器具工程技术研究中心

临床医学工程

影响因子:0.193
ISSN:1674-4659
年,卷(期):2024.31(8)