改良序贯疗法与传统三联疗法治疗幽门螺旋杆菌感染患者的效果与安全性比较
Comparison on the Effects and Safety Between Modified Sequential Therapy and Traditional Triple Therapy in the Treat-ment of Patients with Helicobacter Pylori Infection
钟晨 1胡欣1
作者信息
- 1. 江西省抚州市南丰县人民医院消化内科,江西抚州 344500
- 折叠
摘要
目的 比较改良序贯疗法与传统三联疗法治疗幽门螺旋杆菌(Hp)感染的效果与安全性.方法 60 例Hp感染患者随机分为两组,传统组采用传统三联疗法治疗,改良序贯组采用改良序贯疗法治疗,比较两组的疗效、Hp根除率、不良反应.结果 改良序贯组的治疗总有效率、Hp根除率均明显高于传统组,不良反应总发生率明显低于传统组(P<0.05).结论 与传统三联疗法相比,改良序贯疗法治疗Hp感染患者的效果更佳且安全性更高.
Abstract
Objective To compare the effects and safety between modified sequential therapy and traditional triple therapy in the treatment of patients with Helicobacter pylori(Hp)infection.Methods 60 patients with Hp infection were randomly divided into two groups.The traditional group was treated with traditional triple therapy,and the modified sequential group was treated with modified sequential therapy.The efficacy,Hp eradication rate and adverse reactions were compared between the two groups.Results The total effective rate of treatment and Hp eradication rate of the modified sequential group were significantly higher than those of the traditional group,and the total incidence of adverse reactions was significantly lower than that of the traditional group(P<0.05).Conclusions Compared with traditional triple therapy,modified sequential therapy is more effective and safer in the treatment of patients with Hp infection.
关键词
幽门螺旋杆菌感染/改良序贯法/传统三联疗法/疗效/安全性Key words
Helicobacter pylori infection/Modified sequential therapy/Traditional triple therapy/Efficacy/Safety引用本文复制引用
出版年
2024