阶梯减压术治疗重症颅脑创伤患者的效果及对预后的影响
Effect of Stepwise Decompression in the Treatment of Patients with Severe Craniocerebral Trauma and Its Impact on Prog-nosis
张宏江 1张海涛1
作者信息
- 1. 滑县人民医院神经外科,河南安阳 456400
- 折叠
摘要
目的 探讨颅内压(ICP)监测下的阶梯减压术治疗重症颅脑创伤患者的临床效果.方法 选取 2021 年 4 月至 2023年 4 月我院收治的 100 例重症颅脑创伤患者,随机分为两组各 50 例.观察组采用ICP监测下的阶梯减压术治疗,对照组采用去大骨瓣减压术治疗,比较两组的炎性因子、脑代谢、蛋白代谢及预后.结果 术后 1 周,观察组的hs-CRP、TNF-α水平均低于对照组,TRE、RBP、SVO2、CEO2 均高于对照组(P<0.05).观察组的预后良好率为 80.00%,高于对照组的 56.00%(P<0.05).结论 ICP监测下的阶梯减压术可减轻重症颅脑创伤患者的炎性反应,稳定脑代谢及蛋白代谢水平,改善预后.
Abstract
Objective To explore the clinical effect of stepwise decompression under intracranial pressure(ICP)monitoring in the treatment of patients with severe craniocerebral trauma.Methods 100 patients with severe craniocerebral trauma admitted to our hospital from April 2021 to April 2023 were selected and randomly divided into two groups,with 50 cases in each group.The observation group was treated with stepwise decompression under ICP monitoring,and the control group was treated with large bone flap decompression.The inflammatory factors,brain metabolism,protein metabolism and prognosis were compared between the two groups.Results One week after surgery,the levels of hs-CRP and TNF-α in the observation group were lower than those in the control group,and TRE,RBP,SVO2 and CEO2 were higher than those in the control group(P<0.05).The good prognosis rate in the observation group was 80.00%,higher than 56.00%in the control group(P<0.05).Conclusions Stepwise decompression under ICP monitoring can relieve the inflammatory response of patients with severe craniocerebral trauma,stabilize the levels of brain metabolism and protein metabolism,and improve the prognosis.
关键词
阶梯减压术/颅内压/重症颅脑创伤/预后Key words
Stepwise decompression/Intracranial pressure/Severe craniocerebral trauma/Prognosis引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据