Changes of Coagulation Function Indicators in Patients with Lung Cancer and Their Correlations with Prognosis
Objective To observe the changes of coagulation function indicators in patients with lung cancer and their correlations with prognosis.Methods 96 patients with lung cancer admitted to our hospital from November 2021 to July 2022 were selected as the lung cancer group,and 96 healthy people in the same period were selected as the healthy group.The coagulation function indicators of the two groups were compared.After 1 year of follow-up,the coagulation function indicators of lung cancer patients with different prognosis were compared,and the influencing factors of poor prognosis were analyzed.Results APTT and PT in the lung cancer group were significantly shorter than those in the healthy group,and the FIB and D-D levels were significantly higher than those in the healthy group(P<0.05).In the lung cancer group,APTT and PT in patients with poor prognosis were significantly shorter than those in patients with good prognosis,and the FIB and D-D levels were significantly higher than those in patients with good prognosis(P<0.05).Logistic regression analysis showed that APTT and PT were protective factors(OR<1,P<0.05),and FIB and D-D were independent risk factors(OR>1,P<0.05)for poor prognosis of patients with lung cancer.Conclusions Patients with lung cancer are generally accompanied by abnormal coagulation function.Blood hypercoagulability is an influencing factor for poor prognosis of patients with lung cancer and can be used for prognosis evaluation.
国家科技期刊平台
NSTL
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