首页|降脂消浊汤治疗非酒精性脂肪性肝炎湿热蕴结证的效果及对患者免疫功能的影响

降脂消浊汤治疗非酒精性脂肪性肝炎湿热蕴结证的效果及对患者免疫功能的影响

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目的 探讨降脂消浊汤治疗非酒精性脂肪性肝炎(NASH)湿热蕴结证的效果及对患者免疫功能的影响.方法 选取2021年1月至2023年12月我院收治的120例NASH患者,按照就诊顺序分为两组.对照组采用西药治疗,观察组采用降脂消浊汤治疗.比较两组治疗效果、血脂指标、炎性因子、免疫功能指标.结果 观察组总有效率高于对照组(P<0.05).治疗后,观察组TG、TC、IL-6、TNF-α水平低于对照组(P<0.05).治疗后,观察组CD3+、CD4+、CD4+/CD8+高于对照组,CD8+低于对照组(P<0.05).结论 降脂消浊汤治疗NASH湿热蕴结证的效果确切,可调节血脂代谢及炎性因子分泌,改善患者免疫功能.
Effect of Jiangzhi Xiaozhuo Decoction in the Treatment of Damp-Heat Accumulation Syndrome of Nonalcoholic Steatohep-atitis and the Impact on Immune Function
Objective To explore the effect of Jiangzhi Xiaozhuo Decoction in the treatment of damp-heat accumulation syndrome of nonalcoholic steatohepatitis(NASH)and the impact on immune function.Methods 120 NASH patients admitted to our hospital from January 2021 to December 2023 were selected and divided into two groups according to the treatment order.The control group was treated with western medicine,while the observation group was treated with Jiangzhi Xiaozhuo Decoction.The treatment effect,blood lipid indicators,inflammatory factors and immune function indicators were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the TG,TC,IL-6 and TNF-α levels of the observation group were lower than those of the control group(P<0.05).After treatment,the CD3+,CD4+and CD4+/CD8+of the observation group were higher than those of the control group,and the CD8+was lower than that of the control group(P<0.05).Conclusions Jiangzhi Xiaozhuo Decoction has exact effecti in the treatment of the damp-heat accumulation syndrome of NASH,which can regulate the blood lipid metabolism and the secretion of inflammatory factors,and improve the immune function of patients.

Jiangzhi Xiaozhuo DecoctionNonalcoholic steatohepatitisImmune function

白山岭、赵文

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河南省传染病医院肝病科,河南郑州 450015

河南省传染病医院消化科,河南郑州 450015

降脂消浊汤 非酒精性脂肪性肝炎 免疫功能

河南省医学科技攻关计划联合共建项目

LHGJ20200129

2024

临床医学工程
国家医疗保健器具工程技术研究中心

临床医学工程

影响因子:0.193
ISSN:1674-4659
年,卷(期):2024.31(9)