Clinical Study on Qingfei Huatan Decoction Combined with Procaterol in the Treatment of Children with Pneumonia Asthma Cough
Objective To explore the clinical effect of Qingfei Huatan Decoction combined with procaterol in the treatment of children with pneumonia asthma cough.Methods 78 children with pneumonia asthma cough were divided into reference group(39 cases,treated with procaterol)and study group(39 cases,treated with Qingfei Huatan Decoction combined with procaterol)according to different treatment methods.The clinical efficacy,levels of airway cytokines(TIMP-1,TGF-β1,MMP-9)and adverse reactions were compared between the two groups.Results The total effective rate of treatment in the study group was 94.87％,higher than 79.49％in the reference group(P＜0.05).After 7 days of treatment,the serum TIMP-1 level of the study group was higher than that of the reference group,and the TGF-β1 and MMP-9 levels were lower than those of the reference group(P＜0.05).During the treatment,the incidence of adverse reactions in the study group was 0.00％,which had no statistical difference with 2.56％in the reference group(P＞0.05).Conclusions Qingfei Huatan Decoction combined with procaterol has significant effect in the treatment of children with pneumonia asthma cough,which can significantly reduce the airway hyperresponsiveness of children,and is safe and reliable.
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