首页|IVIM-DWI参数联合DCE-MRI参数对肝癌患者经肝动脉化疗栓塞治疗后复发的预测价值

IVIM-DWI参数联合DCE-MRI参数对肝癌患者经肝动脉化疗栓塞治疗后复发的预测价值

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目的 探讨体素内不相关运动扩散加权成像(IVIM-DWI)参数联合磁共振动态对比增强(DCE-MRI)参数对肝癌患者经肝动脉化疗栓塞(TACE)治疗后复发的预测价值.方法 160例经TACE治疗有效的肝癌患者根据复发情况分为复发组和未复发组,比较两组的IVIM-DWI参数(D、D*、ADC)、DCE-MRI参数(Ktrans、Kep、Ve),分析相关参数对肝癌患者TACE治疗后复发的预测价值.结果 复发组的D低于未复发组,D*、Ktrans、Kep均高于未复发组(P<0.05);两组的ADC、Ve比较,差异无统计学意义(P>0.05).ROC曲线显示,D*、D、Ktrans、Kep联合对肝癌患者TACE治疗后复发具有良好的预测价值(AUC=0.814).结论 IVIM-DWI参数联合DCE-MRI参数可有效预测肝癌患者TACE治疗后的复发情况.
Predictive Value of IVIM-DWI Parameters Combined with DCE-MRI Parameters for Recurrence After Transcatheter Ar-terial Chemoembolization Treatment in Patients with Hepatocellular Carcinoma
Objective To explore the predictive value of intravoxel incoherent motion diffusion-weighted imaging(IVIM-DWI)parameters combined with dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)parameters for recurrence after transcatheter arterial chemoembolization(TACE)treatment in patients with hepatocellular carcinoma.Methods According to the recurrence situation,160 patients with hepatocellular carcinoma who were effective in TACE treatment were divided into the recurrence group and the non-recurrence group.The IVIM-DWI parameters(D,D*,ADC)and DCE-MRI parameters(Ktrans,Kep,Ve)of the two groups were compared,and the predictive value of the relevant parameters for the recurrence of patients with hepatocellular carcinoma after TACE treatment was analyzed.Results The D of the recurrence group was lower than that of the non-recurrence group,and the D*,Ktrans and Kep were higher than those of the non-recurrence group(P<0.05).ROC curve showed that the combination of D*,D,Ktrans and Kep had good predictive value for recurrence after TACE treatment in patients with hepatocellular carcinoma(AUC=0.814).Conclusions IVIM-DWI parameters combined with DCE-MRI parameters can effectively predict the recurrence of patients with hepatocellular carcinoma after TACE treatment.

Intravoxel incoherent motion diffusion-weighted imagingDynamic contrast-enhanced magnetic resonance imagingTranscatheter arterial chemoembolizationRecurrencePredictive value

吕宛平、李波

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南阳市第一人民医院磁共振室,河南南阳 473000

体素内不相关运动扩散加权成像 磁共振动态对比增强 经肝动脉化疗栓塞 复发 预测价值

2024

临床医学工程
国家医疗保健器具工程技术研究中心

临床医学工程

影响因子:0.193
ISSN:1674-4659
年,卷(期):2024.31(10)