血清NT-proBNP、cTnI、Lp-PLA2联合检测对妊娠期高血压孕妇妊娠结局的预测价值
Predictive Value of Combined Detection of Serum NT-proBNP,cTnI and Lp-PLA2 on Pregnancy Outcome of Pregnant Women with Gestational Hypertension
余桂芝 1何畅1
作者信息
- 1. 河南省信阳市第三人民医院医学检验科,河南信阳 464000
- 折叠
摘要
目的 分析血清NT-proBNP、cTnI、Lp-PLA2联合检测对妊娠期高血压孕妇妊娠结局的预测价值.方法 92例妊娠期高血压孕妇根据妊娠结局分为不良结局组、正常结局组,比较两组确诊时的血清NT-proBNP、cTnI、Lp-PLA2水平,评价各指标单独及联合检测对妊娠结局的预测效能.结果 不良结局组的血清NT-proBNP、cTnI、Lp-PLA2水平均高于正常结局组(P＜0.05).ROC曲线显示,血清NT-proBNP、cTnI、Lp-PLA2三项指标联合检测预测妊娠期高血压孕妇妊娠结局的AUC为0.932,高于各指标单独检测.结论 血清NT-proBNP、cTnI、Lp-PLA2联合检测预测妊娠期高血压孕妇妊娠结局的效能较高.
Abstract
Objective To analyze the predictive value of combined detection of serum NT-proBNP,cTnI and Lp-PLA2 on pregnancy outcome of pregnant women with gestational hypertension.Methods 92 pregnant women with gestational hypertension were divided into adverse outcome group and normal outcome group according to the pregnancy outcome.The levels of serum NT-proBNP,cTnI and Lp-PLA2 at the time of diagnosis were compared between the two groups,and the predictive efficacy of single detection and combined detection of the above indicators was evaluated.Results The levels of serum NT-proBNP,cTnI and Lp-PLA2 in the adverse outcome group were higher than those in the normal outcome group(P＜0.05).ROC curve showed that the A UC of combined detection of serum NT-proBNP,cTnI and Lp-PLA2 in predicting pregnancy outcome of pregnant women with gestational hypertension was 0.932,higher than that of single detection of each index.Conclusions The combined detection of serum NT-proBNP,cTnI and Lp-PLA2 has higher efficacy in predicting pregnancy outcome of pregnant women with gestational hypertension.
关键词
NT-proBNP/cTnI/Lp-PLA2/妊娠期高血压/妊娠结局/预测价值Key words
NT-proBNP/cTnI/Lp-PLA2/Gestational hypertension/Pregnancy outcome/Predictive value引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据