Impact of Tirofiban Combined with Ticagrelor on Cardiac Function and Inflammatory Factors of Patients with Coronary Heart Disease
Objective To explore the clinical effect of tirofiban combined with ticagrelor in the treatment of coronary heart disease.Methods 100 patients with coronary heart disease were divided into the reference group(ticagrelor)and the combined group(tirofiban+ticagrelor)according to different treatment methods.The cardiac function,inflammatory factor levels and adverse reactions were compared between the two groups.Results After treatment,LVESd,LVEDd and levels of serum IL-33,TNF-α and IL-6 in the combined group were lower than those in the reference group,and LVEF was higher than that in the reference group(P＜0.05).No significant difference was found in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusions Tirofiban combined with ticagrelor can obviously improve the cardiac function and relieve the inflammatory response of patients with coronary heart disease.
国家科技期刊平台
NSTL
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