Analysis on the Clinical Effect and Short-Term Prognosis of Neoadjuvant Immunotherapy Combined with Chemotherapy in the Treatment of Esophageal Cancer
Objective To analyze the clinical effect and short-term prognosis of neoadjuvant immunotherapy combined with chemotherapy in the treatment of patients with esophageal cancer.Methods A total of 68 patients with esophageal cancer were randomly divided into two groups.The reference group received surgical treatment,and the study group received neoadjuvant immunotherapy combined with chemotherapy on the basis of the reference group.The clinical efficacy,tumor marker levels,recurrence rate and survival rate were compared between the two groups.Results The ORR of the study group was 58.82%,higher than 32.35%of the reference group(P<0.05).After treatment,the levels of serum CA125 and CEA of the study group were lower than those of the reference group(P<0.05).The recurrence rate of the study group was lower than that of the reference group,and the survival rate was higher than that of the reference group(P<0.05).Conclusions Neoadjuvant immunotherapy combined with chemotherapy in the treatment of esophageal cancer can significantly improve the clinical efficacy,reduce the expressions of tumor markers,and improve the short-term prognosis of patients.
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