首页|血府逐瘀汤方加减联合注射用环磷腺苷治疗对冠心病患者心功能及炎性反应的影响

血府逐瘀汤方加减联合注射用环磷腺苷治疗对冠心病患者心功能及炎性反应的影响

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目的 探讨血府逐瘀汤方加减联合注射用环磷腺苷治疗冠心病患者的临床效果.方法 80 例冠心病患者根据治疗方法的不同分为两组.参照组采用注射用环磷腺苷治疗,研究组采用血府逐瘀汤方加减联合注射用环磷腺苷治疗.比较两组的心功能、血清炎性介质以及不良反应.结果 治疗2 周后,研究组的LVEF、CO、CI均高于参照组,血清hs-CRP、TNF-α、TRAF6水平均低于参照组(P<0.05).两组的不良反应总发生率比较,差异无统计学意义(P>0.05).结论 血府逐瘀汤方加减联合注射用环磷腺苷治疗可明显改善冠心病患者的心功能,减轻患者的炎性反应,安全性高.
Impact of Modified Xuefu Zhuyu Decoction Combined with Adenosine Cyclophosphate for Injection Treatment on Cardiac Function and Inflammatory Response of Patients with Coronary Heart Disease
Objective To explore the clinical effect of modified Xuefu Zhuyu decoction combined with adenosine cyclophosphate for injection in the treatment of patients with coronary heart disease.Methods 80 patients with coronary heart disease were divided into two groups according to different treatment methods.The reference group was treated with adenosine cyclophosphate for injection,and the study group was treated with modified Xuefu Zhuyu decoction combined with adenosine cyclophosphate for injection.The cardiac function,serum inflammatory mediators and adverse reactions were compared between the two groups.Results After 2 weeks of treatment,LVEF,CO and CI of the study group were higher than those of the reference group,and the levels of serum hs-CRP,TNF-α and TRAF6 were lower than those of the reference group(P<0.05).No significant difference was found in the total incidence of adverse reactions between the two groups(P>0.05).Conclusions Modified Xuefu Zhuyu decoction combined with adenosine cyclophosphate for injection can obviously improve the cardiac function and relieve the inflammatory response of patients with coronary heart disease,with high safety.

Xuefu Zhuyu decoctionAdenosine cyclophosphateCoronary heart diseaseCardiac functionInflammatory response

孙小菲、陈琳

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郑州仁济医院内科,河南 郑州 450000

血府逐瘀汤方 环磷腺苷 冠心病 心功能 炎性反应

2024

临床医学工程
国家医疗保健器具工程技术研究中心

临床医学工程

影响因子:0.193
ISSN:1674-4659
年,卷(期):2024.31(12)