Analysis on the Relationships of SIRT-1 and PLAGL2 Expressions in Ovarian Cancer Tissue with the Clinical Pathological Parameters and Prognosis of Patients
Objective To analyze the relationships of SIRT-1 and PLAGL2 expressions in ovarian cancer tissue with the clinical pathological parameters and prognosis of patients.Methods 76 patients with ovarian cancer were selected,and the relationships of SIRT-1 and PLAGL2 expressions in cancer tissue with the clinical pathological parameters and prognosis were analyzed.Results Cox analysis showed that FIGO stageⅢ～Ⅳ,low differentiation,lymph node metastasis,and positive expressions of SIRT-1 and PLAGL2 were independent influencing factors for the prognosis of patients with ovarian cancer(P<0.05).Conclusions The positive expression rates of SIRT-1 and PLAGL2 increase significantly in ovarian cancer tissue,and their expressions are related to the clinical pathological parameters and prognosis.
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