一种7.5F自研心腔内超声动物实验
Animal Experiment of a 7.5F Self-Developed Intracardiac Echocardiography
冯文慧 1何精才 1曹琴 1周欣欢1
作者信息
- 1. 深圳心寰科技有限公司,广东 深圳 518101
- 折叠
摘要
目的 验证心腔内超声(Intracardiac Echocardiography,ICE)成像系统应用于动物实验的性能及其安全性.方法 用标准超声体模测试ICE系统的成像深度以及分辨率,再对巴马猪活体进行ICE成像,评估成像视野及分辨率,同时评价导管通过性、调弯操作性及安全性,并与商业化ICE系统进行对比.结果 自研的ICE成像系统最大探测深度≥60 mm,轴向与侧向分辨率均≤1.0 mm.活体ICE成像中,两种导管均于数字减影血管造影引导下顺利经股静脉进入右心房,且通过手柄调整导管头端角度均可显示目标切面.心腔结构清晰可辨,噪声较小,自研ICE系统成像质量与商业化ICE系统接近.操作后实验猪均健康存活,未见介入相关损伤.结论 自研7.5F ICE导管系统性能稳定、安全,操作便利.
Abstract
Objective To verify the performance and safety of intracardiac echocardiography(ICE)imaging system in animal experiments.Methods The imaging depth and resolution of ICE system were tested by standard ultrasonic phantom,then Bama pig was imaged by ICE,and the imaging field and resolution were evaluated.At the same time,the catheter passability,bending maneuverability and safety were evaluated,and compared with the commercial ICE system.Results The self-developed ICE imaging system had a maximum detection depth of≥60 mm and axial and lateral resolution of≤1.0 mm.In vivo ICE imaging,two kinds of catheters successfully entered the right atrium through femoral vein under the guidance of digital subtraction angiography,and the target section could be displayed by adjusting the angle of the catheter tip with the handle.The structure of the cardiac chamber was clear and recognizable,with less noise,and the imaging quality of the self-developed ICE system was close to that of the commercial ICE system.After the operation,all the experimental pigs survived healthily and no intervention-related injuries were found.Conclusion The self-developed 7.5F ICE catheter system is stable,safe and easy to operate.
关键词
心腔内超声/心脏介入手术/相控阵换能器/介入导管Key words
intracardiac echocardiography/cardiac intervention/phase array transducer/intervention catheter引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据