偕二氟烯丙基硅的光催化合成
Photocatalytic synthesis of gem-difluoroallyl-silicons
李智 1杨春晖 2温万柳 2孙蔚青 2和振秀 2陈景超 2樊保敏1
作者信息
- 1. 云南民族大学化学与环境学院,云南昆明 650500
- 2. 云南民族大学民族医药学院,云南昆明 650500
- 折叠
摘要
烯丙基硅化合物是合成创新材料单体或医药中间体的重要化合物和合成中间体.文章报道了4CzIPN作为有机光催化剂催化的硅基羧酸的脱羧偕二氟烯丙基化反应.该反应使用在空气中能够稳定存在且容易大量合成的硅酸作为硅源,在温和的条件下高效合成偕二氟烯丙基硅化合物.结果为制备具有良好官能团相容性的偕二氟烯丙基硅化合物提供了一种快速、简单、经济的光化学合成方法.
Abstract
Allyl silicon compounds are important building blocks for the synthesis of innovative material monomers or medicinal intermediates.Herein,we describe an effective and straightforward decarboxylative difluoroallylation reaction utilizing 4CzIPN as organic photocatalyst.This reaction uses silicic acid as silicon source,which is stable in air and easy to synthesize in large quantities,enabled the efficient synthesis of difluoroallyl silicon compounds under mild conditions.The current reaction has provided a rapid,simple and economical photochemical synthesis method for the preparation of difluoroallylsilyl compounds with good functional group compatibility.
关键词
烯丙基硅基化/偕二氟烯丙基/偕二氟烯烃/烯丙基硅烷/光催化Key words
allylic silylation/gem-difluoroallyl/gem-difluoroalkene/allylsilane/photocatalyzed引用本文复制引用
基金项目
国家自然科学基金(21961045)
国家自然科学基金(22061048)
出版年
2024
NETL
NSTL
万方数据