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短药蒲桃叶子的化学成分研究

Studies on the chemical constituents of the leaves of Syzygium brachyantherum

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利用正反相硅胶柱色谱和 Sephadex LH-20 凝胶柱色谱等分离技术对短药蒲桃(Syzygium brachyantherum)叶子部分化学成分进行研究,运用NMR波谱技术和文献对照鉴定其结构,从中分离鉴定了10 个化合物,分别为 3β,23-O-isopropylidenyl-2a,19a-dihydroxy-urs-12-en-28-oic acid(1)、hyptaic acid B(2)、科罗索酸(3)、软木三萜酮(4)、表木栓醇(5)、粘霉烯醇(6)、daucosterol(7)、(7R,8S)-3,5'-dimethoxy-4',7-epoxy-8,3'-neolignane-5,9,9'-triol(8)、没食子酸甲酯(9)和β-芹子烯(10).其中,化合物1 为新化合物,可能是在分离过程中由化合物2 与丙酮形成的3β,23-缩酮,所有化合物均首次从短药蒲桃中分离得到.
Various separation techniques such as normal and adverse silica gel and Sephadex LH-20 gel column chramatography were used to investigate the chemical constituents from the leaves of Syzygium brachyantherum.In result,ten compounds,including 3β,23-O-isopropylidenyl-2a,19a-dihydroxy-urs-12-en-28-oic acid(1),hyptaic acid B(2),corosolic acid(3),friedelin(4),friedelan-3β-ol(5),3β-hydroxy-5-glutinene(6),daucosterol(7),(7R,8S)-3,5'-dimethoxy-4',7-epoxy-8,3'-neolignane-5,9,9'-triol(8),methyl gallate(9)and β-selinene(10)were isolated and determined and their structures were identified by NMR spectroscopic data and comparison with values reported.Among them,compound 1 was a new ketal produced by 2 and acetone during isolation.All compounds were isolated from S.brachyantherumfor the first time.

MyrtaceaeSyzygium brachyantherumtriterpenoids

卯升丹、许文、刘东豪、贺元彪、赵勇

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云南师范大学化学化工学院,云南昆明 650500

桃金娘科 短药蒲桃 三萜

国家自然科学基金

35160098

2024

云南大学学报(自然科学版)
云南大学

云南大学学报(自然科学版)

CSTPCD北大核心
影响因子:0.663
ISSN:0258-7971
年,卷(期):2024.46(4)