云南化工2024,Vol.51Issue(2) :62-66.DOI:10.3969/j.issn.1004-275X.2024.02.15

磁改性D151阳离子交换树脂纯化黄柏小檗碱

Purification of Berberine from Phellodendron by Magnetic Modified D151 Cationic Exchange Resin

武佳盈 侯梦梦 冯浩恩 张翠利
云南化工2024,Vol.51Issue(2) :62-66.DOI:10.3969/j.issn.1004-275X.2024.02.15

磁改性D151阳离子交换树脂纯化黄柏小檗碱

Purification of Berberine from Phellodendron by Magnetic Modified D151 Cationic Exchange Resin

武佳盈 1侯梦梦 1冯浩恩 1张翠利1
扫码查看

作者信息

  • 1. 黄河科技学院, 河南 郑州 450063
  • 折叠

摘要

采用化学共沉淀法制备磁性树脂,以对小檗碱的吸附率为指标,采用单因素试验和正交试验,考察了母液浓度、pH值、吸附温度和时间对吸附率的影响,并与未磁化的D151 树脂进行对比.试验结果表明,最佳的吸附条件为母液质量浓度为0.015 mg/mL,pH值为8,温度为 35℃,吸附时间为 2.5 h,磁性 D151 树脂的吸附率高达91.11%,未被磁化的D151 树脂的吸附率为85.76%.磁改性D151 阳离子交换树脂用于黄柏中小檗碱的分离速度快,吸附率高,工艺简单.

Abstract

Magnetic resin was prepared by chemical coprecipitation method,the effects of concentration of motherliquor、pH value of solution、adsorption temperature and time on adsorption rate were investigated by single factor test and orthogonal test,taking the adsorption rate of berber-ine as an index,and compared with the unmagnetized D151 resin.The test results show that,the optimum adsorption conditions are as follows:the concentration of mother liquor is 0.015 mg/mL,pH value of solution is 8,the temperature is 35℃,the adsorption time is 2.5 h,the adsorp-tion rate of magnetic D151 resin is as high as 91.11%,and the adsorption rate of unmagnetized D151 resin is 85.76%.Magnetic modified D151 cation exchange resin is used for the separation of Berberine from Phellodendron amurense with high adsorption rate and simple process.

关键词

黄柏/分离/纯化/小檗碱

Key words

Phellodendron/separation/purification/Berberine

引用本文复制引用

基金项目

天然药物化学创新创业示范课(JCXK202301)

河南省重点学科工程项目(教高[2018]119号)

天然药物化学在线课程(ZLG202107)

河南省科技厅科技攻关基金(172102310419)

河南省教育厅自然科学计划基金(16B150006)

出版年

2024
云南化工
云南省化工研究院 云天化集团有限责任公司 云南煤化工集团有限公司 云南省化学化工学会

云南化工

影响因子:0.272
ISSN:1004-275X
参考文献量20
段落导航相关论文