Uncertainty Evaluation for Determination of 31 Anti-infection Drugs in Cosmetics by UPLC-MS/MS
(Objective)The uncertainty of content detection of 31 anti-infection drugs in cosmetics was analyzed and related factors affecting the quantitative detection of cosmetics were analyzed.(Methods)According to the determination of anti-infective drug in cosmetics in Safety and Technical Standards for Cosmetics(2015 Edition),according to JJF 1059.1-2012 Evaluation and Expression of Uncertainty in Measurement and JJF 1135-2005 Evaluation of Uncertainty in Chemical Analysis Measurement,a mathematical model for the determination of 31 anti-infec-tion drugs was established,and the source of uncertainty was analyzed and evaluated.(Results)The measurement uncertainty of this method mainly came from the standard substance and the preparation process of a series of standard working solutions.(Conclusion)The evaluation re-sults can provide a theoretical reference for the determination of anti-infective drugs in Cosmetics.
国家科技期刊平台
NSTL
万方数据
