Application of Ethanol Extract from Hedyotisdiffusa in Cosmetics
Hedyotisdiffusa was extracted by alcohol extraction method.The effects of ethanol extract on tyrosinase,antioxidant capacity,antimicro-bial and moisturizing properties were studied,and its application in cosmetics was evaluated.The results showed that the extract of Hedyotisdiffu-sawill inhibit the activity of tyrosinase,which inhibition rate could reach 71.69% at the concentration of 250 μg/mL.The extract of Hedyotisdif-fusa had a strong scavenging effect on DPPH free radicals,and median clearance mass concentration(EC50)was17.62 μg/mL.The extract of Hedyotisdiffusa had good inhibitory effects on Escherichia coli,Pseudomonas aeruginosa and Staphylococcus aureus.Compared with glycerol,Hedyotisdiffusa has a certain moisturizing effect,which comes from the absorption of external water.Hedyotisdiffusa has good whitening,antioxi-dant,antimicrobial and moisturizing effects,which can be applied in the research and development of cosmetics with corresponding efficacy.