线形聚(ε-己内酯)和星形聚(ε-己内酯)的合成及表征
Synthesis and Characterization of Linear and Star-shaped Poly(ε-caprolactone)
汪林玉 1于保辉 1陈永竹 1宝利军 1彭小琼 1毕韵梅1
作者信息
- 1. 云南师范大学 化学化工学院,云南 昆明 650500
- 折叠
摘要
以辛酸亚锡Sn(Oct)2 为催化剂,分别通过苯甲醇和季戊四醇引发 ε-己内酯(CL)的开环聚合(ROP),制备了线形聚(ε-己内酯)(PCL)和四臂星形聚(ε-己内酯)(S-(PCL)4)).用核磁共振氢谱(1H NMR)表征了聚合物的结构,用凝胶渗透色谱(GPC)测定了它们的相对分子质量.线形聚(ε-己内酯)(PCL)和四臂星形聚(ε-己内酯)(S-(PCL)4)可用后续制备基于聚己内酯的两亲性嵌段共聚物,为可生物降解药物输送载体的开发和应用打下基础.
Abstract
Linear poly(ε-caprolactone)(PCL)and four-arm star-shaped poly(ε-caprolactone)(S-(PCL)4)were prepared by ring-o-pening polymerization(ROP)of ε-caprolactone initiated by benzyl alcohol and pentaerythritol respectively,using stannous octoate Sn(Oct)2 as a catalyst.The structure of the polymers were characterized by 1 H NMR spectra and their molecular weight were determined by gel permeation chromatography(GPC).Linear poly(ε-caprolactone)and four-arm star-shaped polymers(ε-caprolactone)can be used to prepare am-phiphilic block copolymers based on polycaprolactone,which lays a foundation for the development and application of biodegradable drug deliv-ery carriers.
关键词
线形聚(ε-己内酯)/星形聚(ε-己内酯)/开环聚合Key words
Linear poly(ε-caprolactone)/Star poly(ε-caprolactone)/Ring-opening polymerization(ROP)引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据