Determination of Methanol in Baijiu and Wine by Headspace-gas Chromatography Tandem Mass Spectrometry
To establish qualitative and quantitative method for the determination of methanol in Baijiu and wine by headspace-gas chromatogra-phy tandem mass spectrometry(HS-GC/MSMS).The sample is directly loaded into a headspace bottle without pre-treatment and automati-cally injected.The headspace equilibrium temperature is 80.0 ℃,the constant temperature time is 35 minutes,the salting-out agent is 2 g NaCl.It uses split injection with a split ratio of 100∶1,uses an electron impact source(EI)as the ion source,and uses multiple response monito-ring(MRM)mode for analysis.It is confirmed that the accuracy of internal standard method for Baijiu and external standard method for wine is higher.The linear relationship of methanol has good in the range of 0.201416～10.0708 mg/L and 10.0708～402.832 mg/L,with correlation coefficient R2 greater than 0.999,the recovery rate is 97.51％～102.05％,and the precision RSD is 0.583％～3.814％(n=6).This method is simple,sensitive,less interference,high accuracy,suitable for rapid detection of methanol in Baijiu and wine.
MethanolBaijiuWineHeadspace-Gas Chromatography Tandem Mass SpectrometryMultiple Response Monitoring
万方数据
维普
