首页|静电纺丝纳米纤维支架在骨组织工程中的应用研究

静电纺丝纳米纤维支架在骨组织工程中的应用研究

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骨缺损和骨疾病的治疗一直是临床医学的重要研究方向。尽管传统的移植手术在治疗这些问题上取得了较好效果,但它仍然受到一些限制,包括供体数量有限、免疫排斥反应以及引发的移植并发症等问题,这些因素限制了传统移植手术的广泛应用。因此,骨组织工程作为一种新兴的治疗方法备受研究者的关注。静电纺丝纳米纤维支架因其独特的结构特性和生物活性而被认为是骨组织工程领域的理想材料。然而,为了实现最佳的骨再生效果,如何优化静电纺丝纳米纤维支架的设计和应用仍有许多问题需要深入研究。通过文献综述了静电纺丝纳米纤维支架的特点以及在骨组织工程中的应用,期望为开发更有效、更安全的骨组织工程支架提供参考。
Application Research of Electrospun Nanofiber Scaffold in Bone Tissue Engineering
The treatment of bone defects and bone diseases has long been a significant area of focus in clinical medicine.Although traditional grafting surgeries have been effective in addressing these issues,they are subject to limitations such as donor shortage,immune rejection,and transplantation-related complications,which restrict the broader application of traditional grafting.Therefore,bone tissue engineering has gar-nered significant attention as an emerging treatment method among researchers.Electrospun nanofiber scaffolds are considered ideal materials in the field of bone tissue engineering due to their unique structural characteristics and bioactivity.However,in order to achieve optimal bone re-generation,there are still many issues that require in-depth research concerning the design and application of electrospun nanofiber scaffolds.This paper introduces the features of electrospun nanofiber scaffolds and their applications in bone tissue engineering.It aims to provide a refer-ence for developing more effective and safer bone tissue engineering scaffolds.

ElectrospinningNanofiber ScaffoldBone Tissue EngineeringBone RegenerationBone Defect

田春燕、强琳辉、许士奇、李坤、魏秋江、褚夫环

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承德医学院 生物医学工程系,河北 承德 067000

静电纺丝 纳米纤维支架 骨组织工程 骨再生 骨缺损

2024

云南化工
云南省化工研究院 云天化集团有限责任公司 云南煤化工集团有限公司 云南省化学化工学会

云南化工

影响因子:0.272
ISSN:1004-275X
年,卷(期):2024.51(10)