Research progress in refractory wounds of diabetes foot ulcers
Lower limb complications of patients with diabetes have become an increasingly important public health problem in the world.As one of the most serious complications,diabetic foot ulcerationshave significant morbidity,amputation and mortality rates and are costly to treat.At present,due to the influence of the high sugar environ-ment,the disease is relatively complex,the pathogenesis has not been fully explored,and the lack of precise treat-ment strategies cannot completely overcome this chronic disease.The etiology mechanism and complications of dia-betes foot ulcer needs to be determined and evaluated to provide correct treatment,which is a key to reduce the risk of lower limb amputation.The high threat factors,pathogenesis and current treatment strategies of diabetes foot ulcer were reviewed in this article.