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基于无质量弹簧结构的肺组织动态建模及变形预测方法

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在放射治疗中,人体呼吸运动将导致肺部发生变形,其上肿瘤随之发生的变形和空间运动对放射治疗的精准性和安全性产生不利影响.结合计算机断层扫描(CT)影像三维建模技术和呼吸力学原理,提出了一种基于无质量弹簧结构的肺部动态变形建模及变形预测方法.首先在在放疗前根据医学影像信息建立肺部模型,然后根据呼吸预测肺部的变形及其上肿瘤的运动.实验结果表明,根据预测方法得出的肺部变形与连续医学影像观测下的变形相一致,预测值与观测值的误差在合理范围之内.研究能够在常规医学条件下准确、高效地预测呼吸运动影响下肺部的变形与力学特性,为后续肿瘤位移补偿研究提供理论和方法支撑.
Dynamic modeling and deformation prediction method of lung tissuebased on massless spring mechanism
In radiation therapy,the respiration may cause lung deformation. The subsequent deformation and spatial movement of tumors on the lung adversely affect the accuracy and safety of radiation therapy. By combining computed tomography (CT) image 3D modeling technology and respiratory mechanics principle,a new method of lung dynamic deformation modeling and deformation prediction based on a massless spring mechanism is proposed in this article. First,a lung model is formulated,which is based on medical image information before radiotherapy. Then,the deformation of the lung and the movement of the tumor on it are predicted based on respiration. The experimental results show that the lung deformation obtained by this method is consistent with the deformation observed under continuous medical imaging. The error between the predicted value and the observed value is within a reasonable range. This study can accurately and efficiently predict lung deformation and mechanical properties under the influence of respiratory movement under conventional medical conditions. It provides theoretical and method support for subsequent research on tumor displacement compensation.

lung 3D modelingmassless spring modeldynamic modelingdeformation prediction

张来喜、朱盛杰、朱艳梅、马凯威、徐丰羽

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兰州理工大学机电工程学院 兰州 730050

南京邮电大学自动化学院 南京 210046

肺部三维建模 无质量弹簧模型 动态建模 变形预测

2024

仪器仪表学报
中国仪器仪表学会

仪器仪表学报

CSTPCD北大核心
影响因子:2.372
ISSN:0254-3087
年,卷(期):2024.45(10)