Acid dye fixing agent SE for silk fabric was synthesized using hydroxypropyl methacrylate, methacrylic acid, triethylene tetramine and epoxy chloropropane as main materials. The fixation process was analyzed and the optimum parameters were obtained as fol ows: the optimal dosage of the fixing agent SE was 30 g/L, liquor ratio was 1∶20, the fixation temperature and time was 60 ℃ and 30 min respectively. After drying, the fabric was cured at 150 ℃ for 3 min. The fixed silk fabric had fairly good color fastness to wet and dry rubbing, which can reach grade 4 or over grade 4. And the fastness to soaping and perspiration also could reach grade 4.