Determination of seventeen perfluorinated compounds in water by solid phase extraction coupled with HPLC-ESI-MS/MS
A method for the determination of 17 kinds of perfluorinated compounds(PFCs)in water was established by solid phase extraction,ultra-high performance liquid chromatography-electrospray series mass spectrometer.The samples were filtered by glass fiber filter membrane and pre-treated with WAX extraction column solid phase extraction column.The column temperature and the flow rate were set at 40℃and 0.3 mL/min.Ammonium acetate and acetonitrile were used as mobile phases for separation by gradient elution procedure,and the samples were determined by UHPLC-tandem mass spectrometry(MRM)negative ion mode.Quantitative by internal standard method.By optimizing the conditions of pretreatment and test parame-ters of the experiment,the standard curve drawing results showed that the linearity of the method was good(R＞0.999)for 17 kinds of perfluorinated compounds in the range of 0-100 μg/L.The relative standard devia-tion of the actual labeled samples of low,medium and high mass concentrations ranged from 0.53%to 12.00%,and the recovery rate ranged from 70.7%to 114.0%.The test results showed that the method could be applied to the actual detection work.
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